Doses of Verapamil work differently in different people. The dose should therefore be made on an individual basis, weighing the possible benefit of a higher dose with possible side effect risks. The Verapamil dose should always be individualized by starting at low doses and increasing based on response. Giving someone .Verapamil for the treatment of migraine headaches: an introduction. Verapamil is a calcium channel blocker. It is also used by some as a migraine prevention medication, although it has not been approved by the U.S. Food and Drug Administration for that purpose..INTRODUCTION. Migraine headaches can be debilitating if patients cannot control or minimize the symptoms, and they can substantially impair the quality of life. However, migraines can often be successfully controlled by the avoidance of triggers, lifestyle changes, and abortive treatment. In patients in whom these .Ten of 12 patients, eight of 14 patients, and patients showed improvement, with all stu.s finding verapamil significantly more effective than placebo in migraine prophylaxis. Research comparing 240 mg/day with 320 mg/day dosing found 320 mg/day significantly more effective in reducing migraine frequency..
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