Tolterodine tartrate is a white, crystalline powder with a molecular weight of 475.6. The pKa value is 9.87 and the solubility in water is 12 mg/mL. It is soluble in methanol, slightly soluble in ethanol, and practically insoluble in toluene. The partition coefficient Log D between n-octanol and water is 1.83 at pH 7.3. DETROL LA .Results of several 12-week placebo-controlled stu.s in patients with an overactive bladder indicate that tolterodine tartrate mg twice daily as conventional tablets is more effective than placebo in relieving urinary symptoms e.g., urinary frequency, urgency, urge incontinence . Patients receiving tolterodine tartrate 2 .For patients with mild to moderate hepatic impairment Child-Pugh Class A or B or severe renal impairment CCr 10-30 mL/min , the recommended dose of tolterodine tartrate extended-release capsules is 2 mg once daily. Tolterodine tartrate extended-release .Find patient medical information for Tolterodine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings..
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Long-acting Oral agents: preferred of the non-selective agents Detrol LA Tolterodine LA mg daily. Similar efficacy compared to Oxybutinin XR.
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