A number of strategies are available for switching between antidepressants Table 2 ., Close clinical observation and caution is required with all approaches, as some patients may respond idiosyncratically and serious complications can occur. Individual patient factors and illness factors may require .The recommendations in this table are based on clinical experience, product information, empirical evidence and recommendations from other guidelines. It may be necessary to modify the switching process depending on patient, illness and interacting drug variables, determined by the patient 's clinical progress..Switching Antidepressants part of ; an app 'switchtabellen ' is available . To see the consequences of a switch between antidepressants click in the crosstable below: the switch is made "from" vertical "to" horizontal . First read the general considerations concerning switching antidepressants .Taper switch after a washout: gradually withdraw the first antidepressant, then start the new antidepressant after a washout period. 4. Cross-tapering: taper the first antidepressant usually over 1-2 week or longer , and build up the dose of the new antidepressant simultaneously. The following table is intended for general .
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Introduction. There exist longstanding concerns that antidepressant drugs produce modest clinical improvement, with only a minority of patients achieving full .