The potentiation process does not have to be invasive. Hydrocodone and oxycodone, for example, can be evaporated using cold water extraction. The liquid can be put into a nasal sprayer. A concentrated solution can also be added to chewing gum with a liquid center; the liquid with concentrated drug may then be added .Rangrz. 20-11-2008, 22:39. As Jam said, it will potentiate opioids and CNS depressants, it self is a CNS depressant, but not one that produces any sort of euphoria. 1 's but it 's not worth it. Methocarbamol is a shit muscle relaxant but is decent for mixing with opiates especially if you put a benzo in the mix..In 2002, some of the most commonly abused drugs included oxycodone, hydrocodone, hydromorphone, morphine, codeine, clonazepam, alprazolam, lorazepam, Do they require carisoprodol for muscle spasms, or can they use a medication with an alternative pharmacology, such as methocarbamol, .If an opiate agonist is initiated in a patient taking a skeletal muscle relaxant, use a lower initial dose of the opiate and titrate to clinical response. Atropine; Difenoxin: Moderate Concurrent administration of diphenoxylate/difenoxin with methocarbamol can potentiate the CNS-depressant effects of diphenoxylate/difenoxin..
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