Clonidine, an imidazoline-derivative hypotensive agent is a centrally-acting 2 -adrenergic agonist. It crosses the blood-brain barrier and acts in the hypothalamus to induce a decrease in blood pressure. It may also be administered as an epidural infusion as an adjunct treatment in the management of severe cancer pain .
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THE MECHANISM OF ACTION OF CLONIDINE R. BLOCH, P. BOUSQUET, J. FELDMAN and J. SCHWARTZ Institut de Pharmacologie et de Mdecine Exprimentale..
This chapter reviews the mechanism of action of Clonidine. The structure of the Clonidine molecule has been established from anysis of its NMR spectra. In.
Clonidine trade names Catapres, Kapvay, Nexiclon, Clophelin, and others is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, .