Can You Cut Extended Release Tablets In Half

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5 Answers - Posted in: nausea/vomiting, tramadol, dosage, prescription - Answer: Yes Jim you may cut it in half and take 25mg. Be cautious of .Any medication that has XR extended release is not meant to be altered in any way shape form or fashion, the drug is meant to release an amount over a 24 hour .Hi. Now you have got me worried as well. I have been on percocets for about 6 months. I frequently break them in half because I don't like to take too much meds..Initially, 75 mg PO once daily. Alternatively, 37.5 mg PO once daily can be given for days to allow for tolerability before increasing to 75 mg PO once daily..

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