Biphasic Drug

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Biphasic drug delivery system is an innovative drug delivery system for oral administration which is composed of one fast release layer and one sustain release layer. Layered tablet concept is utilized to develop controlled and sustained release formulations..A study was carried out into the biphasic drug release properties of film-coated paracetamol tablets. The tablet cores were formulated without a disintegrant and film-coated with a coating formulation consisting of pectin, chitosan and hydroxypropylmethylcellulose in a ratio of 6:1:0.37. The tablet cores and the film-coated .